Webinar: Impact of Freeze-Drying Conditions on Stability of Food
and Pharmaceutical Materials

Date: Thursday, 02 April 2020

Understanding the mechanism of sugar-protein interactions is of great interest in controlling protein functionalities. Proteins are often co-lyophilized in sugar matrices for added stability. The formulation’s phase transitions (i.e. glass transition, crystallization point, melting point) are commonly used to evaluate the physical stability of amorphous materials. These transitions can be greatly affected by the moisture content and therefore, investigation of the water sorption behavior for these protein-sugar formulations is paramount in determining the ultimate product stability.

In this webinar, the presenter showed the study conducted on moisture induced phase transitions for several co-lyophilized protein-sugar mixtures have been investigated over a wide humidity range.

Presenter:

Meishan Guo is an Application Engineer in Surface Measurement Systems. Since joining SMS in 2018, She has been working on surface charctherization of solid materials, including fibre, powder and film samples, using Dynamic Vapour Soprtion (DVS) and Inverse Gas Chromatography (iGC-SEA) as the techniques. Meishan obtained her Master’s Degree in Chemical Engineering at Imperial College London in December 2017. Her research project was focused on investigating the properties of fragrance molecules with solid substrates by diffusion and sorption. She also received her Bacherlor’s Degree in Chemical Technology at the Hong Kong Polytechnic University and in Chemistry at Sun Yat-sen University in June 2016.

Dr. Majid Naderi received his MSc degree in Petrochemicals and his doctorate in the synthesis of novel catalysts (sponsored by Shell) from the University of Manchester Institute of Science and Technology (U.M.I.S.T.), Manchester, U.K. He joined Surface Measurement Systems in 2002 using his background in physical chemistry and its application to the characterization and development of inorganic solids. Dr Naderi is the Associate Director of Science Applications for Surface Measurement Systems with responsibility for the application of Dynamic Vapor Sorption (DVS) and Inverse Gas Chromatography (iGC) for materials characterization using a broad range of materials including, pharmaceuticals, catalysts and polymers. Dr Naderi has delivered a number of international lectures and is author and co-author of more than 40 scientific papers and posters as well as a chapter book on the methods for measuring BET surface area.